Industrial freeze-dryers IMA Lyomax

Freeze-drying involves removal of solvent such that the molecular structure of the active ingredient of the drug is least disturbed, thus providing a dried drug product that is stable over time. 

Beyond Limits

Although one of the oldest techniques in the pharmaceutical industry for the preservation of unstable materials, there has been an increasing demand for lyophilized products and equipment, in particular in the last decade. In fact today, about half of all sterile injectables are lyophilized.

The freeze-drying process of today demands increased process control, with reduced processing time augmented with upgrades in equipment to remain compliant with a changing regulatory landscape. To accommodate such growth, IMA LIFE uses its in-depth process knowledge to make freeze drying faster, safer, cheaper, and compatible with all industry requirements and challenges.

LYOMAX configurable options and custom designs provide the optimal solution for each application.

LYOMAX meets the highest possible technical requirements, the strictest standards of the global licensing authorities, and comply with all the current guidelines such as GAMP, cGMP, FDA etc.

LYOMAX Highlights

1. Machine sizes from 1 m2 to 100 m2.

2. Configurations including integral condenser, external condenser, two-story and pass through designs.

3. Two stage reciprocating semi-hermetic/screw compressors/liquid nitrogen refrigeration system.

4. Shelf cooling to -55/70°C and condenser cooling to -75/120°C. HFC/LN2 refrigerants.

5. Integrated automatic, semi-automatic and manual loading/unloading systems.

6. Vacuum measurements with capacitance manometers.

7. VERISEQ® advanced technology using sterile liquid nitrogen to control the nucleation process during pharmaceutical freeze drying.

Industrial freeze-dryers IMA Lyomax on manufacturer site